I've contacted 2 additional Interventional Radiologists for second opinions. Both will review my scans and consult via Telehealth. This should happen in May.
ETA:
In the meantime, I'm on month 3 of the Venixxa (aka Disomin+Hesperidin MPFF) supplement for vein health, 600 mg twice a day, and I do believe it is helping a bit. And last week I started a 2.5 mg weekly dose of tirzepatide (aka Zepbound) since reading this article about 1 woman who got relief for PGAD: https://pmc.ncbi.nlm.nih.gov/articles/P ... /?hl=en-US ...Thank you, Violet, for sharing that!!
Potter MRI
Re: Potter MRI
Last edited by 29Mari on Tue May 05, 2026 3:14 am, edited 4 times in total.
PGAD began 2010. Left vulva deep pain&arousal. Lower left ab pain/tugging.
2020 PFPT failed.
2023: Prolapse surgery, More PT.
2024: Trigger point injections helped to some extent.
2025: Dry needling helps! Inconclusive nerve blocks. Potter MRI shows pelvic varices but no nerve entrapments.
2026: Trying Venixxa supplement for vein health and it seems to be helping my PGAD! Also doing a trial of Zepbound (tirzepatide) to see if it helps my PGAD.
2020 PFPT failed.
2023: Prolapse surgery, More PT.
2024: Trigger point injections helped to some extent.
2025: Dry needling helps! Inconclusive nerve blocks. Potter MRI shows pelvic varices but no nerve entrapments.
2026: Trying Venixxa supplement for vein health and it seems to be helping my PGAD! Also doing a trial of Zepbound (tirzepatide) to see if it helps my PGAD.
Re: Potter MRI
Hope you get some valuable info, Mari.
Violet
Violet
PNE since 2002. Started from weightlifting. PNE surgery from Dr. Bautrant, Oct 2004. Pain now is usually a 0 and I can sit for hours on certain chairs. No longer take medication for PNE. Can work full time and do "The Firm" exercise program. 99% cured from PGAD. PNE surgery was right for me but it might not be for you. Do your research.
Re: Potter MRI
A small update with a bit of hope for PGAD sufferers:
I was chatting with another woman on a different site who suffers chronic daily PGAD with worsening flares, and she volunteered that hers mostly resolved with a different GLP-1, Wegovy, that she was prescribed for a separate issue (weight loss, I think). She plans to taper back down to the lowest effective dose for her PGAD. I hope she keeps me updated.
As for me, I took my 3rd dose of Zepbound (tirzepatide) yesterday, still at the lowest dose 2.5 mg. I have not had any severe flares since starting it 2 weeks ago. But any positive effects for the PGAD may be confused with my improvement from a vein health supplement I started 3 months ago. I started the supplement after a diagnosis of vulvar varicosities that were seen on my recent Potter MRI and a subsequent MRV. Because the supplement, Venixxa (aka Diosmin + Hesperidin MPFF), is helping so much, I really do suspect my PGAD has a vascular component. But the PGAD is there brewing just under the surface, always, daring me to do anything that would cause a flare. So I will continue Zepbound and increase to 5 mg at one month on!
I was chatting with another woman on a different site who suffers chronic daily PGAD with worsening flares, and she volunteered that hers mostly resolved with a different GLP-1, Wegovy, that she was prescribed for a separate issue (weight loss, I think). She plans to taper back down to the lowest effective dose for her PGAD. I hope she keeps me updated.
As for me, I took my 3rd dose of Zepbound (tirzepatide) yesterday, still at the lowest dose 2.5 mg. I have not had any severe flares since starting it 2 weeks ago. But any positive effects for the PGAD may be confused with my improvement from a vein health supplement I started 3 months ago. I started the supplement after a diagnosis of vulvar varicosities that were seen on my recent Potter MRI and a subsequent MRV. Because the supplement, Venixxa (aka Diosmin + Hesperidin MPFF), is helping so much, I really do suspect my PGAD has a vascular component. But the PGAD is there brewing just under the surface, always, daring me to do anything that would cause a flare. So I will continue Zepbound and increase to 5 mg at one month on!
PGAD began 2010. Left vulva deep pain&arousal. Lower left ab pain/tugging.
2020 PFPT failed.
2023: Prolapse surgery, More PT.
2024: Trigger point injections helped to some extent.
2025: Dry needling helps! Inconclusive nerve blocks. Potter MRI shows pelvic varices but no nerve entrapments.
2026: Trying Venixxa supplement for vein health and it seems to be helping my PGAD! Also doing a trial of Zepbound (tirzepatide) to see if it helps my PGAD.
2020 PFPT failed.
2023: Prolapse surgery, More PT.
2024: Trigger point injections helped to some extent.
2025: Dry needling helps! Inconclusive nerve blocks. Potter MRI shows pelvic varices but no nerve entrapments.
2026: Trying Venixxa supplement for vein health and it seems to be helping my PGAD! Also doing a trial of Zepbound (tirzepatide) to see if it helps my PGAD.
Re: Potter MRI
Thanks for the update, Mari. Such good news!! Interesting (and wonderful!) that that supplement seems to be helping. And it's so nice to get insight from that about the cause of the PGAD. Glad you also started a GLP-1. (So great that there now are multiple cases of this working!) But, yeah, I guess it might be hard to know if it is helping since you already seemed to improve from the supplement. But maybe it will help remove that sense that it is brewing under the surface, as you put it. Keep us posted!
April
April